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The Immortal Life of Henrietta Lacks

The Immortal Life of Henrietta Lacks

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Author: Rebecca Skloot
Publisher: Crown
Category: Book

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Rating: 4.5 out of 5 stars 102 reviews

Media: Hardcover
Edition: 1
Pages: 384
Number Of Items: 1
Shipping Weight (lbs): 1.4
Dimensions (in): 9.4 x 6.2 x 1.7

ISBN: 1400052173
Dewey Decimal Number: 616.02774092
EAN: 9781400052172
ASIN: 1400052173

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Features:
  • ISBN13: 9781400052172
  • Condition: NEW
  • Notes: Brand New from Publisher. No Remainder Mark.

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Editorial Reviews:

Amazon.com Review
Amazon Best Books of the Month, February 2010: From a single, abbreviated life grew a seemingly immortal line of cells that made some of the most crucial innovations in modern science possible. And from that same life, and those cells, Rebecca Skloot has fashioned in The Immortal Life of Henrietta Lacks a fascinating and moving story of medicine and family, of how life is sustained in laboratories and in memory. Henrietta Lacks was a mother of five in Baltimore, a poor African American migrant from the tobacco farms of Virginia, who died from a cruelly aggressive cancer at the age of 30 in 1951. A sample of her cancerous tissue, taken without her knowledge or consent, as was the custom then, turned out to provide one of the holy grails of mid-century biology: human cells that could survive--even thrive--in the lab. Known as HeLa cells, their stunning potency gave scientists a building block for countless breakthroughs, beginning with the cure for polio. Meanwhile, Henrietta's family continued to live in poverty and frequently poor health, and their discovery decades later of her unknowing contribution--and her cells' strange survival--left them full of pride, anger, and suspicion. For a decade, Skloot doggedly but compassionately gathered the threads of these stories, slowly gaining the trust of the family while helping them learn the truth about Henrietta, and with their aid she tells a rich and haunting story that asks the questions, Who owns our bodies? And who carries our memories? --Tom Nissley


Amazon Exclusive: Jad Abumrad Reviews The Immortal Life of Henrietta Lacks

Jad Abumrad is host and creator of the public radio hit Radiolab, now in its seventh season and reaching over a million people monthly. Radiolab combines cutting-edge production with a philosophical approach to big ideas in science and beyond, and an inventive method of storytelling. Abumrad has won numerous awards, including a National Headliner Award in Radio and an American Association for the Advancement of Science (AAAS) Science Journalism Award. Read his exclusive Amazon guest review of The Immortal Life of Henrietta Lacks:

Honestly, I can't imagine a better tale.

A detective story that's at once mythically large and painfully intimate.

Just the simple facts are hard to believe: that in 1951, a poor black woman named Henrietta Lacks dies of cervical cancer, but pieces of the tumor that killed her--taken without her knowledge or consent--live on, first in one lab, then in hundreds, then thousands, then in giant factories churning out polio vaccines, then aboard rocket ships launched into space. The cells from this one tumor would spawn a multi-billion dollar industry and become a foundation of modern science--leading to breakthroughs in gene mapping, cloning and fertility and helping to discover how viruses work and how cancer develops (among a million other things). All of which is to say: the science end of this story is enough to blow one's mind right out of one's face.

But what's truly remarkable about Rebecca Skloot's book is that we also get the rest of the story, the part that could have easily remained hidden had she not spent ten years unearthing it: Who was Henrietta Lacks? How did she live? How she did die? Did her family know that she'd become, in some sense, immortal, and how did that affect them? These are crucial questions, because science should never forget the people who gave it life. And so, what unfolds is not only a reporting tour de force but also a very entertaining account of Henrietta, her ancestors, her cells and the scientists who grew them.

The book ultimately channels its journey of discovery though Henrietta's youngest daughter, Deborah, who never knew her mother, and who dreamt of one day being a scientist.

As Deborah Lacks and Skloot search for answers, we're bounced effortlessly from the tiny tobacco-farming Virginia hamlet of Henrietta's childhood to modern-day Baltimore, where Henrietta's family remains. Along the way, a series of unforgettable juxtapositions: cell culturing bumps into faith healings, cutting edge medicine collides with the dark truth that Henrietta's family can't afford the health insurance to care for diseases their mother's cells have helped to cure.

Rebecca Skloot tells the story with great sensitivity, urgency and, in the end, damn fine writing. I highly recommend this book. --Jad Abumrad


Look Inside The Immortal Life of Henrietta Lacks

Click on thumbnails for larger images

Henrietta and David Lacks, circa 1945.
Elsie Lacks, Henrietta’s older daughter, about five years before she was committed to Crownsville State Hospital, with a diagnosis of “idiocy.”
Deborah Lacks at about age four.
The home-house where Henrietta was raised, a four-room log cabin in Clover, Virginia, that once served as slave quarters. (1999)
Main Street in downtown Clover, Virginia, where Henrietta was raised, circa 1930s.


Margaret Gey and Minnie, a lab technician, in the Gey lab at Hopkins, circa 1951.
Deborah with her children, LaTonya and Alfred, and her second husband, James Pullum, in the mid-1980s.
In 2001, Deborah developed a severe case of hives after learning upsetting new information about her mother and sister.
Deborah and her cousin Gary Lacks standing in front of drying tobacco, 2001.
The Lacks family in 2009.




Product Description
Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.

Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.

Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia—a land of wooden slave quarters, faith healings, and voodoo—to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.

Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family—past and present—is inextricably connected to the dark history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.

Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance? 
          
Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.



Customer Reviews:
Showing reviews 1-5 of 102
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5 out of 5 stars Captivating, engrossing, fascinating, heartbreaking, englightening...ALL in one stellar book!   January 16, 2010
Living it up (Peach State)
157 out of 175 found this review helpful

This is hand's down one of the best books I've read in years and I wish I could give it more stars. It is going to be difficult to capture exactly what makes this book so outstanding and so captivating, but I'm going to give it my best shot.

First of all I want to say I am STUNNED that this is the author's first book. She has poured ten years of her heart, soul, mind and her life in general in this book. What she has given birth to in that long period of labor is worthy of her sacrifice and honors Henrietta Lacks and her family.

Other reviews have given the outline of this amazing story. What I want to stress is that Ms. Skloot has navigated the difficult terrain of respecting Mrs. Lacks and her family, while still telling their story in a very intimate, thorough, factual manner. What readers may not know is that the Lacks family isn't just a "subject" that the author researched. This is a real family with real heartaches and real challenges whose lives she entered into for a very long season. The Lacks' family has truly benefitted from the author's involvement in their life and that is something I am very appreciative of. I believe that Ms. Skloot was able to give Henrietta's daughter, Deborah, a real sense of healing, deliverance, peace and identity that she had been searching for her whole life...that story alone would have made the book for me.

It would have been very easy for the author to come across as condescending or patronizing or possibly as being exploitive as the wrote about a family that is poor and uneducated. Instead the story is infused with compassion and patience as she not only takes the family along with her on a journey to understand their current situation and the ancestor whose life was so rich in legacy but poor in compensation; she educates the family in the process. I get the sense that the author grew to genuinely love Henrietta and her family. I am in awe of this level of commitment.

The author has managed to explain the complex scientific information in a way that anyone can comprehend and be fascinated by. The author's telling of the science alone and the journey of Henrietta's immortal cells (HeLa) would have made the book a worthy read in itself. Ms. Skloot and Henrietta captured me from page one all the way to the final page of the book. I read it in one pass and I didn't want it to end.

The author manages to beautifully tell multiple stories and develops each of those stories so well that you can't help but be consumed by the book. This is the story of Henrietta. It is the story of her sweet and determined daughter, Deborah. It is the story of the extended Lacks family and their history. It is a story of race/poverty/ignorance and people who take advantage of that unfortunate trifecta. It is a story about science and ethics. It is a story that should make each of us reflect on the sacrifices made by individual humans and animals that have allowed us to benefit so much from "modern" medicine. It is a story about hope and perseverance. It is a story about love and healing.

I cannot imagine a single person I know who wouldn't love this book and benefit from reading it. I will be purchasing the final copy of the book and am looking forward to reading the book again.

I am counting the days til Ms. Skloot writes another book and can't wait to attend one of her upcoming lectures. A fan is born!



5 out of 5 stars Thank you for this beautiful tribute to Henrietta Lacks   February 6, 2010
E. Jacobs
49 out of 53 found this review helpful

Wow. This book should be required reading for scientists and students of life. The true story of Henrietta Lacks and her family has finally been told, beautifully, in this book. The book encompasses science, ethics, and the story of a family who was terribly wronged in the pursuit of scientific research. I could gush about this book for pages but I'll try first to hit the main points of why this book is so remarkable in list form for the sake of brevity:


1. The author clearly developed a strong relationship with the Lacks family, which was absolutely critical to ensuring the story was told accurately and with the respect to Henrietta Lacks that was so deeply deserved.

2. The storytelling is amazingly moving despite the need to convey a lot of scientific information. It reads like fiction.

3. Ms. Skloot's research into the science is impeccable.

4. The book is FAIR. It presents the unvarnished truth, obtained DIRECTLY from as many prinicpal people involved in the story as is humanly possible. It would have been easier to simplify the story into heroes vs. villians, but Ms. Skloot deftly handles all sides of the story.


For some detail: I have worked with HeLa cells in the past, but did not know even the barest information about the story of Henrietta Lacks until a few years ago. It simply was not common knowledge, until a few less ethical folks released her name and medical records to the public. This obviously should not have been done without the express permission of the Lacks family, which Ms. Skloot obtained. In the past, others have not been as ethical. The book covers Ms. Lacks' early life, how her cells came to be harvested, and what happened to both the cells and her family afterward.

The contributions of HeLa cells to science are absolutely staggering and cannot be over-stated. The sections where the science was described were clear and accurate. With the story of Ms. Lacks' family interwoven, this book was fairly close to perfect. I found myself moved to tears several times because of the fate of the Lacks family and Henrietta's daughter's indomitable spirit. I do not think anyone but Ms. Skloot could have written this book. She worked with the family for over a decade in order to get the story right. This was critical, as the family had been wronged too many times in the past.

Thank you for this astounding work of art. I will be donating to the Henrietta Lacks foundation in honor of the entire family, and I hope many others will read the book and be similarly moved.



5 out of 5 stars 2010 Non-Fiction Award Winner?   January 8, 2010
gail powers (Harbor County, MI and N. Naples, FL)
111 out of 130 found this review helpful

As I recall this book was categorized as CANCER, I believe it might be more aptly described as science based non-fiction. In the last two decades I've seen occasional news items alluding to human cells taken from a black woman in the 1950's that have been replicated millions of times. The cells are referred to as HeLa and on the face of it I wouldn't have thought there was much of a story behind the extraction of these cells and their use by the biomed industry. However, this book dispells that rather naive assumption completely and puts a name and a face, a family, and a story behind the contents of many petri dishes and slides. THE IMMORTAL LIFE OF HENRIETTA LACKS explains how the cells were obtained, replicated, distributed, and used without informed consent of the owner and family by John Hopkins and how they benefitted mankind w/o compensation to the family. Author Skloot tells the story of a family victimized by socioeconomic conditions and racism that can't get fundamental things like health coverage while these cells make a lot of money for the health establishment. It is a disturbing read that will stay with the reader long after the book is finished. It may also make the reader take a long hard look at the need for standardized health care in our society among many other things.


5 out of 5 stars Absolutely superb   January 18, 2010
Daffy Du (Del Mar, CA United States)
40 out of 48 found this review helpful

Equal parts history, psychological drama, expose and character study, Rebecca Skloot's gripping debut is a deeply affecting tour de force that effortlessly bridges the gap between science and the mainstream.

Her subject is the multilayered drama behind one of the most important--and in many ways, problematic--advances of modern medicine. Captivated by the story of Henrietta Lacks, a poor African-American woman whose cervical cancer cells (dubbed HeLa) were the first immortalized cells grown in culture and became ubiquitous in laboratories around the world, Skloot set out to learn more about the person whose unwitting "donation" of the cells transformed biomedical research in the last century. Her research ultimately spanned a decade and found her navigating (and to some extent, mediating) more than 50 years of rage over the white scientific establishment's cavalier mistreatment and exploitation of the poor, especially African Americans.

Skloot deftly weaves together an account of Lacks's short life (she died at age 31) and torturous death from an extremely aggressive form of cancer; the parallel narrative concerning her cells; and the sometimes harrowing, sometimes amusing chronicle of Skloots's own interactions with Lacks's surviving (and initially hostile and uncooperative) family members. Moving comfortably back and forth in time, the richly textured story that emerges brings into stark relief the human cost of scientific progress and leaves the reader grappling with many unanswered questions about the ethics of the scientific endeavor, past and present. While the goals of biomedical research may be noble, how they are achieved is not always honorable, particularly where commercialization of new technologies is at stake. Skloot offers a clear-eyed perspective, highlighting the brutal irony of a family whose matriarch was a pivotal figure in everything from the development of Jonas Salk's polio vaccine to AIDS research to cancer drugs, yet cannot afford the very medical care their mother's cells helped facilitate, with predictable consequences.

The LA Times book review section named Skloot one of its four "Faces to Watch in 2010," an honor that, based on "The Immortal Life of Henrietta Lacks" is well-deserved.

Five stars--it was hard to put down this compelling, admirable and eminently readable book.



5 out of 5 stars Hands down one of the most compelling book I have read   February 4, 2010
S. J. Koblentz (Columbus, OH United States)
13 out of 16 found this review helpful

If you mention "HeLa cells" to most people, you are going to draw a blank look or a "what did you say?" But HeLa cells are the basis for some of the most amazing science discovers in the field of molecular biology and medicine today.

Rebecca Skloot's work is not a dry review of what the cells are or how they were used. Skloot uses this magnificent line of cells as the spring to dive into the live that created them, that of Henrietta Lacks, a black woman who ultimatly died from the cancer that was created by these same sells.

Skloot digs deep into a life shrouded in mystery - a woman who was deeply loved and missed by her family members once she died, and the science industry that took her cells, propagated them in the name of scientific discovery, and then used and confused her family in the years afterward. The poverty of Mrs. Lacks childhood, and her family plays a significant role in how communications and silence between blacks and whites, males and females, educated and under educated occured leaving Lack's children - especially her youngest daughter - feeling as if the world had a better grasp on who Herietta was than they do.

What emerges is the painfully poignent story of a family left behind and used and tired of people calling them up to tell them who Henrietta Lacks was, and defining her only as a vessel by which the HeLa cells were created. The author diviates from that one track thought process by involving the reader with yearning that she had to know the woman who made these things possible. As the reader I wanted to know this woman, to have coffee with her, to hear her talk about her thoughts, her aspirations and her fears.

The prose of this book is readable and it is compelling. In all honesty, the last book that grabbed my attention as this book did to me was the DaVinci Code.

The Immortal Life of Henrietta Lacks will give a greater appreciation for the woman that she was and will raise ethical questions in your mind about life, race, education, poverty and our own control over what happens to tissues taken and examined in our own lifetimes.

This is a great book!


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